Conversion of Oleic Acid to Linoleic Acid

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Conversion of oleic acid to linoleic acid.

Reports from this laboratory have described the formation of palmitoleic and oleic acids from their saturated counterparts by enzyme systems of yeast (2, 3). For introducing a double bond into the 9,lO position of the aliphatic chain, the desaturating enzymes, acting on the coenzyme A derivatives of the fatty acids, require reduced triphosphopyridine nucleotide, and molecular oxygen as hydrogen...

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The Stereospecific Conversion of Stearic Acid to Oleic Acid.

In several enzyme systems that catalyze the desaturation of stearic acid, oleic acid (cis-Ag-octadecenoic acid) is the sole product and the reaction is therefore characterized by positional and geometrical stereospecificity. We now have found that the desaturating system of Corynebacterium diphtheriae has the further property of selectively removing 1 particular hydrogen atom from each pair of ...

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Conversion of Linoleic Acid Hydroperoxide to Hydroxy,

We have carried out a study of the reaction of 13Irydroperoxy-9-cis, 11-trans-octadecadienoic acid (linoleic acid hydroperoxide) with hematin. The major products are erythro-ll-hydroxy-l2,13-epoxy-S-octadecenoic acid, threo11-hydroxy12,13-epoxy-9-0~tadecenoic acid, 9,12,13-trihydroxy-lO-octadecenoic acid, 13-keto-9,ll-octadecadienoic acid, and 13-hydroxy-9,ll-octadecadienoic acid. Several minor...

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Oleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes.

BACKGROUND Oleic acid is the principal fatty acid of olive oil composition and is reported to play a crucial role in its healthy aspects. However, the detailed mechanism of action is poorly understood. AIMS This study aims to elucidate the role of oleic acid in calcium signaling in rat thymocytes, in comparison to linoleic and linolenic acid. METHODS Fatty acids were applied to thymocytes i...

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Small differences in the effects of stearic acid, oleic acid, and linoleic acid on the serum lipoprotein profile of humans.

BACKGROUND Studies have suggested that oleic and stearic acids, as well as oleic and linoleic acids, have comparable effects on the serum lipoprotein profile. If so, then substituting these three 18-carbon fatty acids for each other would result in similar effects on the serum lipoprotein profile. OBJECTIVE The aim of this study was to compare simultaneously the effects of stearic, oleic, and...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1961

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)64164-x